About 3 results found for searched term "330-54-1" (0.308 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M6849 | JNJ 63533054 | GPR/FFAR |
| JNJ-63533054 is a potent, selective, orally active GPR139 agonist.JNJ-63533054 is more selective for GPR139 than other GPCR, ion channel and transporter proteins.JNJ-63533054 can cross the blood-brain barrier (BBB). | ||
| M8594 | BRD3308 | HDAC |
| BRD3308 is a highly selective HDAC3 inhibitor with an IC50 of 54 nM. BRD3308 is 23 times more selective to HDAC3 than HDAC1 (IC50:1.26 μM) or HDAC2 (IC50:1.34 μM). BRD3308 inhibits pancreatic β cell apoptosis induced by inflammatory cytokines or glucolipid toxic stress and increases functional insulin release. BRD3308 also activates HIV-1 transcription and disrupts HIV-1 latency. | ||
| M24927 | Lodapolimab | PD-1/PD-L1 |
| LY3300054 | ||
| Lodapolimab (LY3300054) is an IgGλ anti-PD-1 monoclonal antibody. | ||
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