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 About 1 result found for searched term "310456-65-6" (0.291 seconds)

Cat.No.  Name Target
M8679 IMR-1 Notch
IMR-1 is a first-in-class, cell-permeable inhibitor of the Notch transcription activation complex, with an IC50 of 26 μM. IMR-1 prevents Maml1 from recruiting to the Notch ternary complex (NTC) in chromatin, inhibits transcription of Notch target genes, and has antitumor activity.



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