About 1 result found for searched term "2649400-34-8" (0.221 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M40697 | NX-5948 | PROTAC |
| BTK-IN-24 | ||
| NX-5948 (BTK-IN-24) is an orally active, blood-brain barrier-penetrating, BTK-targeting degradation agent for the study of B-cell malignancies and autoimmune diseases. NX-5948 induces specific BTK protein degradation by the cereblon E3 ligase (CRBN) complex without degradation of other cereblon neo-substrates. NX-5948 mediates potent anti-inflammatory activity via BTK degradation with resultant inhibition of B cell activation. | ||
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