About 1 result found for searched term "25127-29-1" (0.08 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M19274 | Crebanine | Akt |
| Crebanine, an alkaloid from Stephania venosa, induces G1 arrest and apoptosis in human cancer cells. Crebanine exhibits anti-inflammatory activity via suppressing MAPKs and Akt signaling. Crebanine also possesses antiarrhythmic effect. Furthermore, Crebanine can inhibit the PI3K/Akt/mTOR pathway and generate reactive oxygen species, thereby blocking tumour proliferation and migration. In animal studies, Crebanine has also demonstrated central and peripheral analgesic and anti-inflammatory activity. | ||
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