About 1 result found for searched term "2492382-37-1" (1.044 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M45311 | EGFR-IN-57 | EGFR/HER2 |
| EGFR-IN-57 is a potent, orally active EGFR-TK inhibitor with an IC50 value of 0.054 µM. EGFR-IN-57 also inhibits VEGFR-2, CK2α, topoisomerase IIβ, and tubulin polymerization with an IC50 value of 0.087, 0.171, 0.13, and 3.61 µM, respectively. In addition, EGFR-IN-57 induced G2/M and pre-G1 cycle arrest and apoptosis in cancer cells. | ||
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