About 1 result found for searched term "2460133-35-9" (0.454 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M29661 | BMS-986251 | ROR |
| BMS-986251 is an orally active and selective RORγt inverse agonist with an EC50 of 12 nM for RORγt GAL4. BMS-986251 inhibits IL-17 with an EC50 of 24 nM in human whole blood assay. BMS-986251 demonstrates robust efficacy in mouse acanthosis and Imiquimod-induced models (preclinical models of psoriasis). | ||
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