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 About 1 result found for searched term "243984-11-4" (0.119 seconds)

Cat.No.  Name Target
M4838 TAK-242 (Resatorvid) TLR
Resatorvid; CLI-095
Resatorvid (TAK-242) is a selective TLR4 signaling inhibitor. Resatorvid inhibited the production of NO, TNF-α and IL-6 with IC50 values of 1.8 nM, 1.9 nM and 1.3 nM, respectively. Resatorvid down-regulates the expression of MyD88 and TRIF signaling molecules downstream of TLR4. Resatorvid inhibits autophagy and plays a key role in a variety of inflammatory diseases.



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