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 About 1 result found for searched term "2375432-47-4" (0.121 seconds)

Cat.No.  Name Target
M58581 MS4322 PROTAC
YS43-22
MS4322 (YS43-22) is a specific PRMT5 PROTAC degrader. MS4322 reduces the PRMT5 protein level with a DC50 of 1.1 μM in MCF-7 cells. MS4322 inhibits the methyltransferase activity of PRMT5 with an IC50 of 18 nM. MS4322 promotes ubiquitination and degradation of PRMT5.



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