About 1 result found for searched term "2375432-47-4" (0.121 seconds)
Cat.No. | Name | Target |
---|---|---|
M58581 | MS4322 | PROTAC |
YS43-22 | ||
MS4322 (YS43-22) is a specific PRMT5 PROTAC degrader. MS4322 reduces the PRMT5 protein level with a DC50 of 1.1 μM in MCF-7 cells. MS4322 inhibits the methyltransferase activity of PRMT5 with an IC50 of 18 nM. MS4322 promotes ubiquitination and degradation of PRMT5. |
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