About 1 result found for searched term "2304621-31-4" (0.201 seconds)
Cat.No. | Name | Target |
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M11519 | IMT1 | Mitochondrial Related |
IMT1 is the first, specific and non-competitive inhibitor of human mitochondrial RNA polymerase (POLRMT). IMT1 induces conformational changes in POLRMT that block substrate binding and transcription in a dose-dependent manner in vitro. IMT1 reduced deoxynucleoside triphosphate levels and citric acid cycle intermediates, resulting in significant depletion of cellular amino acid levels. |
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