About 1 result found for searched term "2227429-65-2" (0.128 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M29381 | ADH-6 | p53 |
| ADH-6 is a tripyridylamide compound. ADH-6 abrogates self-assembly of the aggregation-nucleating subdomain of mutant p53 DBD. ADH-6 targets and dissociates mutant p53 aggregates in human cancer cells, which restores p53's transcriptional activity, leading to cell cycle arrest and apoptosis. ADH-6 has the potential for the research of cancer diseases. | ||
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