About 1 result found for searched term "2166558-11-6" (0.21 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M29316 | JNJ-55308942 | P2 Receptor |
| JNJ-55308942 is a high-affinity, selective, brain-penetrant P2X7 functional antagonist (hP2X7: IC50=10 nM, Ki=7.1 nM; rP2X7: IC50=15 nM, Ki=2.9 nM). JNJ-55308942 is orally bioavailable, binds to brain P2X7 and blocks IL-1β release from adult rodent brain. | ||
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