About 1 result found for searched term "2131089-46-6" (0.133 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M24934 | Ontorpacept | Others |
| TTI-621 | ||
| Ontorpacept (TTI-621) is a soluble fusion protein that consists of the human SIRPα N-terminal (1-118) linked to the Fc region of human IgG1. The N-terminal (1-118)-fragment of ontorpacept is a binding domain for CD47 which is an inhibitor of phagocytosis by macrophages. Ontorpacept is a CD47-blocking checkpoint inhibitor with antitumor activity. | ||
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