About 1 result found for searched term "2055776-17-3" (0.121 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M29145 | PF-06445974 | PDE |
| PF-06445974, a promising positron emission tomography (PET) lead, has exquisite potency at PDE4B with an IC50 <1 nM. The IC50 values are 36, 4.7 and 17 nM for PDE4D, PDE4A and PDE4C, respectively. PF-06445974 has good selectivity over PDE4D, excellent brain permeability, and a high level of specific binding in the "cold tracer" study. | ||
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