About 1 result found for searched term "1715025-32-3" (0.089 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M10733 | Rineterkib | ERK |
| Rineterkib (compound B) is an orally active inhibitor of ERK1/2 that exerts an antiproliferative effect by activating mutations in the MAPK pathway. This activity is particularly associated with KRAS-mutant non-small cell lung cancer, BRAF-mutant non-small cell lung cancer, KRAS-mutant pancreatic cancer, KRAS-mutant colon cancer, and KRAS-mutant ovarian cancer. | ||
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