About 1 result found for searched term "171335-80-1" (1.742 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M66155 | Exatecan | Topoisomerase |
| DX-8951 | ||
| Exatecan (DX-8951) is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM. Exatecan significantly inhibits the proliferation of several cancer cell lines, with mean GI50s of 2.02 ng/mL, 2.92 ng/mL, 1.53 ng/mL, and 0.877 ng/mL for breast cancer cells, colon cancer cells, stomach cancer cells and lung cancer cells, respectively. | ||
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