About 1 result found for searched term "164204-38-0" (0.122 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M7137 | Phosphoramidon disodium salt | Neprilysin (NEP) |
| Phosphoramidon disodium salt is a microbial metabolite and an inhibitor of the specific metalloproteases thermolysin, endothelin-converting enzyme (ECE), neutralizing peptidase (NEP) and angiotensin-converting enzyme (ACE), with IC50s of 0.4 μg/mL, 3.5 μM, 0.034 μM and 78 μM, respectively. Phosphoramidon disodium salt also prevented the degradation of amyloid β-peptide and increased Aβ levels in rodents. | ||
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