About 1 result found for searched term "1629013-22-4" (0.122 seconds)
Cat.No. | Name | Target |
---|---|---|
M28726 | GSK3368715 | Histone Methyltransferase |
EPZ019997 | ||
GSK3368715 (EPZ019997) is an orally active, reversible, and S-adenosyl-L-methionine (SAM) uncompetitive type I protein arginine methyltransferases (PRMTs) inhibitor (IC50=3.1 nM (PRMT1), 48 nM (PRMT3), 1148 nM (PRMT4), 5.7 nM (PRMT6), 1.7 nM (PRMT8)). GSK3368715 (EPZ019997) produces a shift in arginine methylation states, alters exon usage, and has strong anti-cancer activity. |
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