About 1 result found for searched term "1494684-28-4" (0.127 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M28536 | Risovalisib | PI3K |
| CYH33 | ||
| Risovalisib (CYH33) is an orally active, highly selective PI3Kα inhibitor with IC50s of 5.9 nM/598 nM/78.7 nM/225 nM against α/β/δ/γ isoform, respectively. Risovalisib inhibits phosphorylation of Akt, ERK and induces significant G1 phase arrest in breast cancer cells and non-small cell lung cancer (NSCLC) cells. Risovalisib has potent activity against solid tumors. | ||
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