About 1 result found for searched term "147098-18-8" (0.123 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M28512 | Rosuvastatin Sodium | HMG-CoA Reductase |
| ZD 4522 Sodium; X-Plended Sodium; Crestor Sodium | ||
| Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. Rosuvastatin Sodium potently blocks hERG current with an IC50 of 195 nM. Rosuvastatin Sodium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Sodium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels. | ||
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