About 1 result found for searched term "145158-71-0" (0.124 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M58580 | Tegaserod | 5-HT Receptor |
| Tegaserod is an orally active serotonin receptor 4 (5-HT4R) agonist and a 5-HT2B receptor antagonist. Tegaserod has pKis of 7.5, 8.4 and 7.0 for human recombinant 5-HT2A, 5-HT2B and 5-HT2C receptors, respectively. Tegaserod causes tumor cell apoptosis, blunts PI3K/Akt/mTOR signaling and decreases S6 phosphorylation. | ||
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