About 1 result found for searched term "1370032-20-4" (0.139 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M45399 | CUR5g | Autophagy |
| CUR5g is a potent autophagy inhibitor that selectively inhibits autophagosome degradation in cancer cells by blocking autophagosome-lysosome fusion. CUR5g also prevents STX17 from being recruited to autophagosomes through a UVRAG-dependent mechanism, resulting in the inability of autophagosomes to fuse with lysosomes. In addition, CUR5g enhances the in vitro and in vivo anticancer effects of cisplatin in A549 cells. | ||
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