About 1 result found for searched term "1354691-97-6" (0.12 seconds)
Cat.No. | Name | Target |
---|---|---|
M43397 | Leniolisib phosphate | PI3K |
Leniolisib (CDZ173) phosphate is a first-in-class, potent and selective PI3Kδ inhibitor with an IC50 value of 11 nM.Leniolisib is more selective for PI3K-δ than PI3K-α (28-fold), PI3K-β (43-fold) and PI3K-γ (257-fold). -γ (257-fold). In a cellular assay, Leniolisib decreased pAKT pathway activity and inhibited the proliferation and activation of B and T cell subsets. |
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