About 1 result found for searched term "1352066-68-2" (0.123 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M10374 | AMG 232 | Mdm2 |
| Navtemadlin ; KRT-232 | ||
| AMG 232 is an extremely potent MDM2 inhibitor (SPR KD = 0.045 nM, SJSA-1 EdU IC50 = 9.1 nM), with remarkable pharmacokinetic properties and in vivo antitumor activity in the SJSA-1 osteosarcoma xenograft model (ED50 = 9.1 mg/kg). *The compound is unstable in solutions, freshly prepared is recommended | ||
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