About 3 results found for searched term "130-15-4" (0.119 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M14640 | 1,4-Naphthoquinone | Others |
| 1,4-Naphthoquinone is a potential pharmacophore for inhibition of both MAO (monoamine oxidase) and DNA topoisomerase activities, this latter associated with antitumor activity. | ||
| M57288 | Sorafenib-d3 | Raf |
| Donafenib; Bay 43-9006-d3 | ||
| Sorafenib-d3 (Donafenib) is a deuterium-labeled Sorafenib, it is the first deuterium-generation tumor suppressor small molecule. Sorafenib is a multikinase inhibitor IC50s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively. | ||
| M28509 | KB130015 | Thyroid Hormone Receptor |
| KB015 | ||
| KB130015 (KB015) is an orally active and potent ThRα and ThRβ (Thyroid Hormone Receptor) inhibitor, with IC50 values of 4.5 and 5.1 μM, respectively. KB130015 has antiarrhythmic properties. KB130015 markedly slows the kinetics of inactivation of Na+ channels. KB130015 opens large-conductance Ca2+-activated K+ channels and relaxes vascular smooth muscle. | ||
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