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 About 2 results found for searched term "128-13-2" (0.135 seconds)

Cat.No.  Name Target
M6047 Ursodiol Animal Modeling
UDCA;Ursodeoxycholic acid; UDCS;Ursodeoxycholate; Ursodiol
Ursodiol reduces cholesterol absorption and is used to dissolve (cholesterol) gallstones with an IC50 of 0.22 μM. Ursodeoxycholic acid (UDCA), which reduces FXR and closes the ACE2 channel. It can be used to construct animal models of cholelithiasis.
M13718 Onvansertib PLK
PCM-075; NMS-1286937; NMS-P937
Onvansertib (PCM-075, NMS-1286937, NMS-P937) is a first-in-class, third-generation, oral, highly selective PLK1 inhibitor that induces tumor cell arrest in the G2/M phase and triggers apoptosis. It has a median IC50=136nM against a variety of CRC cell lines and inhibits xenograft models such as HT-29, HCT-116, and Colo-205 well.



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