About 1 result found for searched term "1223403-58-4" (0.181 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M6151 | Larotrectinib (LOXO-101) | Trk |
| ARRY-470, larotrectinib | ||
| Larotrectinib (LOXO-101) is a potent, ATP competitive TRK inhibitor with IC50s in low nanomolar range for inhibition of all TRK family members in binding and cellular assays, with 100x selectivity over other kinases, with 2 to 20 nM cellular potency against the TRKA, TRKB, and TRKC kinases. | ||
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