About 1 result found for searched term "1221186-53-3" (0.082 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M9001 | TEPP-46 | Pyruvate Kinase |
| ML-265; ML265 | ||
| Ml-265 (TEPP-46) is an effective activator of pyruvate kinase M2 (PKM2). ML265 induces the more active tetrameric state of PKM2 and the X-ray co-crystal structure shows that the activator binds at the dimer-dimer interface between two subunits of PKM2. TEPP-46 also induces a decrease in the intracellular levels of acetyl-coA, lactate, ribose phosphate and serine. | ||
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