116-45-0 - Search Results | AbMole BioScience

About 6 results found for searched term "116-45-0" (0.136 seconds)

Cat.No.	Name	Target
M20029	WAY-114506	Others
	WAY-114506 is a amyloid beta modulator
M56200	ML 145	GPR/FFAR
	ML 145 is a selective and competitive human GPR35/CXCR8 antagonist with an IC50/EC50 of 20.1 nM.
M55777	Sulfabrom	Antibiotic
	Sulfabrom (N 3517; Sulfabromomethazine) is a long-acting Sulfonamide that is used for the treatment of coccidiosis and various bacterial infections in the poultry, swine and cattle.
M30111	ABT-100	Farnesyl Transferase
	ABT-100 is a potent, highly selective and orally active farnesyltransferase inhibitor. ABT-100 inhibits cell proliferation (IC50s of 2.2 nM, 3.8 nM, 5.9 nM, 6.9 nM, 9.2 nM, 70 nM and 818 nM for EJ-1, DLD-1, MDA-MB-231, HCT-116, MiaPaCa-2, PC-3, and DU-145 cells, respectively), increases apoptosis and decreases angiogenesis. ABT-100 possesses broad-spectrum antitumor activity.
M30394	AS-041164	PI3K
	AS-041164 is a potent, selective and orally active PI3Kγ isoform inhibitor with an IC50 of 70 nM. AS-041164 shows less activity against PI3Kα, PI3Kβ, and PI3Kδ (IC50s of 240 nM, 1.45 μM, and 1.70 μM, respectively). AS-041164 has anti-inflammatory effects.
M42215	AZ 11645373	P2 Receptor
	AZ11645373 is a highly selective and potent antagonist at human P2X7 receptors, AZ11645373 inhibits ATP-evoked IL-1β release from lps-activated THP-1 cells , with an IC50 value of 90 nM.