About 5 results found for searched term "112-14-1" (0.121 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2128 | AZ3146 | Kinesin |
| AZ 3146 | ||
| AZ3146 is a potent and selective monopolar spindle 1 (Mps1) kinase inhibitor with IC50 of 35 nM. | ||
| M18914 | Octyl acetate | Others |
| Octyl acetate | ||
| M28201 | Quilseconazole | Antifungal |
| VT-1129 | ||
| Quilseconazole (VT-1129) is a potent, orally active fungal Cyp51 (lanosterol 14-α-demethylase) inhibitor, binds tightly to cryptococcal CYP51, but weakly inhibits humans CYP450 enzymes. | ||
| M29384 | TL13-112 | PROTAC |
| TL13-112 is a potent and selective ALK-PROTAC degrader and inhibits ALK activity with an IC50 value of 0.14 nM. TL13-112 also prompts the degradation of additional kinases including Aurora A, FER, PTK2 and RPS6KA1 with IC50 values of 8550 nM, 42.4 nM, 25.4 nM, and 677 nM, respectively. TL13-112 is comprised of the conjugation of Ceritinib and the Cereblon ligand of Pomalidomide. | ||
| M30026 | UC-112 | IAP |
| UC-112 is a novel potent IAP(Inhibitor of apoptosis) inhibitor. UC-112 potently inhibit cell growth in two human melanoma (A375 and M14) and two human prostate (PC-3 and DU145) cancer cell lines(IC50=0.7-3.4 uM). | ||
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