About 1 result found for searched term "1062149-33-0" (0.184 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M24544 | Enavatuzumab | TNF Receptor |
| PDL192; ABT-361 | ||
| Enavatuzumab (PDL192; ABT-361) is a humanized IgG1 monoclonal antibody targeting the receptor of TNF-like weak inducer of apoptosis (TWEAK). TWEAK (Fn14; TNFRSF12A), the natural ligand of the TWEAK receptor (TweakR), stimulates multiple cellular responses. Enavatuzumab induces tumor growth inhibition through direct TweakR signaling and antibody dependent cell-mediated cytotoxicity (ADCC). Enavatuzumab can actively recruits and activates myeloid effectors to kill tumor cells. | ||
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