About 1 result found for searched term "1050477-31-0" (0.138 seconds)
Cat.No. | Name | Target |
---|---|---|
M9957 | Finerenone | Mineralocorticoid Receptor |
BAY94-8862 | ||
Finerenone (BAY 94-8862) is a third generation selective, oral active, non-steroidal halocorticoid receptor (MR) antagonist (IC50=18 nM). Finerenone showed good selectivity (>500-fold) compared to glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (AR). Finerenone has potential applications in the study of heart and kidney diseases, such as type 2 diabetes and chronic kidney disease. |
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