( )-JQ1 - Search Results | AbMole BioScience

About 5 results found for searched term "( )-JQ1" (0.039 seconds)

Cat.No.	Name	Target
M2167	(+)-JQ1	Epigenetic Reader Domain
	JQ1; Verteporfin
	(+)-JQ1 is a BET bromodomain inhibitor that acts on BRD4(2) with an IC50 of 33 nM and binds to all bromodomain domains in the BET family, but not to bromodomain domains outside the BET family. JQ1 down-regulates CD47 expression through a C-MYC-mediated pathway, and JQ1 down-regulates CD47 expression through a C-MYC-mediated pathway.
M6096	JQ-1 carboxylic acid	Epigenetic Reader Domain
	(+)-JQ-1 carboxylic acid
	(+)-JQ1 carboxylic acid, the carboxylic acid form of (+)-JQ1, is a potent BET bromodomain inhibitor for downregulating PD-L1 expression on the surface of tumor cells. JQ-1 carboxylic acid can be used as a precursor to synthesize PROTACs, which targets BET bromodomains.
M10388	(+)-JQ1 PA	Epigenetic Reader Domain
	(+)-JQ1 PA is a derivative of the Bromodomain and extra-terminal (BET) inhibitor JQ1 with IC50 of 10.4 nM.
M13817	(R)-(-)-JQ1 Enantiomer	Epigenetic Reader Domain
	(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1. (+)-JQ1 potently decreases expression of both BRD4 target genes, whereas (R)-(-)-JQ1 Enantiomer has no effect.
M57677	(+/-)-JQ1	Others
	(+/-)-JQ1