About 1 result found for searched term "(R)-DRF053 dihydrochloride" (0.139 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M45315 | (R)-DRF053 dihydrochloride | Casein Kinase |
| (R)-DRF053 dihydrochloride is a potent inhibitor of casein kinase 1 (CK1), CDK1/cyclin B, and CDK5/p25, with IC50s of 14 nM, 220 nM, and 80 nM, respectively.(R)-DRF053 dihydrochloride prevented the production of CK1-dependent amyloid-β in cellular models. In addition, (R)-DRF053 dihydrochloride prevented the production of CK1-dependent amyloid-β in cell models. | ||
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