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Y06036

Cat. No. M20742

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Y06036 Structure

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Quality Control & Documentation
Biological Activity

Y06036 (compound 6i) is a potent and selective inhibitor of BET with antitumor activity. Y06036 binds to the BRD4(1) bromodomain with Kd of 82 nM.

Chemical Information
Molecular Weight 427.27
Formula C16H15BrN2O5S
CAS Number 1832671-96-1
Solubility (25°C) DMSO 85 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Maofeng Zhang, et al. J Med Chem. Structure-Based Discovery and Optimization of Benzo[ d]isoxazole Derivatives as Potent and Selective BET Inhibitors for Potential Treatment of Castration-Resistant Prostate Cancer (CRPC)

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  Catalog
Abmole Inhibitor Catalog




Keywords: Y06036 supplier, Epigenetic Reader Domain, inhibitors, activators

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