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X-Gluc Dicyclohexylamine

Cat. No. M10568
X-Gluc Dicyclohexylamine Structure
Synonym:

X-BETA-D-GLUCOSIDE

Size Price Availability Quantity
50mg USD 174  USD174 In stock
100mg USD 312  USD312 In stock
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Quality Control & Documentation
Biological Activity

X-Gluc Dicyclohexylamine is used as a reagent to detect β-glucuronidase, an enzyme produced by the E. Coli bacterium; is widely used in molecular biology experiments to mark and select the expression of target genes (GUS reporter system).

Chemical Information
Molecular Weight 521.79
Formula C20H26BrClN2O7
CAS Number 18656-96-7
Solubility (25°C) DMSO 25 mg/mL
DMF 25 mg/mL
Storage 2-8°C, protect from light, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

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