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Wiskostatin

Cat. No. M7489

All AbMole products are for research use only, cannot be used for human consumption.

Wiskostatin Structure
Size Price Availability Quantity
5mg USD 98  USD98 In stock
10mg USD 140  USD140 In stock
25mg USD 260  USD260 In stock
50mg USD 440  USD440 In stock
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Quality Control & Documentation
Biological Activity

Wiskostatin is a inhibitor of neural Wiskott-Aldrich syndrome protein (N-WASP) activity. Wiskostatin interacts with the regulatory GTPase-binding domain of N-WASP. Wiskostatin inhibits activation of Arp2/3 complex by maintaining N-WASP in an inactive conformation. Wiskostatin also inhibits PIP2-induced actin polymerization (EC50 ~ 4μM).

Chemical Information
Molecular Weight 426.15
Formula C17H18Br2N2O
CAS Number 253449-04-6
Solubility (25°C) DMSO 22 mg/mL
Storage Powder -20°C
References

[1] Borsch-Haubold, et al. J Biol Chem. Direct inhibition of cyclooxygenase-1 and -2 by the kinase inhibitors SB 203580 and PD 98059.

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Keywords: Wiskostatin supplier, inhibitors, activators

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