VIT-2763

Cat. No. M29214

All AbMole products are for research use only, cannot be used for human consumption.

Size	Price	Availability
5mg	USD 350 USD350	In stock
10mg	USD 540 USD540	In stock
50mg	USD 1500 USD1500	In stock

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Quality Control & Documentation

Purity: ≥99.0%
COA
MSDS

Product Information

Biological Activity

VIT-2763, an oral ferroportin inhibitor, inhibits hepcidin binding to ferroportin and blocks iron efflux. VIT-2763 has the potential in the treatment of β-thalassemia.

Chemical Information

Molecular Weight	408.43
Formula	C21H21FN6O2
CAS Number	2095668-10-1
Form	Solid
Solubility (25°C)	DMSO 125 mg/mL (ultrasonic)
Storage	Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month

References

[1] Arielle L Langer, et al. Hematology Am Soc Hematol Educ Program. β-Thalassemia: evolving treatment options beyond transfusion and iron chelation

[2] John Porter, et al. Expert Rev Hematol. Oral ferroportin inhibitor vamifeport for improving iron homeostasis and erythropoiesis in β-thalassemia: current evidence and future clinical development

[3] Alexandros Makis, et al. Biology (Basel). Novel Therapeutic Advances in β-Thalassemia

[4] Naja Nyffenegger, et al. Int J Mol Sci. The Oral Ferroportin Inhibitor VIT-2763 Improves Erythropoiesis without Interfering with Iron Chelation Therapy in a Mouse Model of β-Thalassemia

[5] Frank Richard, et al. Am J Hematol. Oral ferroportin inhibitor VIT-2763: First-in-human, phase 1 study in healthy volunteers

Catalog

Keywords: VIT-2763 supplier, Ferroportin, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.

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VIT-2763

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