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Vipivotide tetraxetan (PSMA-617) is a potent prostate-specific membrane antigen (PSMA) inhibitor with Ki value of 0.37 nM, it is used to make 177Lu-PSMA-617, which is a radioactive molecule to fight cancer. PSMA-617 has a high inhibition potency (equilibrium dissociation constant Ki=2.34±2.94 nM on LNCaP; Ki=0.37±0.21 nM enzymatically determined) and highly efficient internalization into LNCaP cells are demonstrated.
| Molecular Weight | 1042.14 |
| Formula | C49H71N9O16 |
| CAS Number | 1702967-37-0 |
| Solubility (25°C) | DMSO ≥ 100 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related PSMA Products |
|---|
| EC1169
EC1169 is a specific PSMA ligand that inhibits the growth of PSMA-positive cells. |
| Glu-urea-Glu-NHS ester
Glu-urea-Glu-NHS ester is an active NHS Glu-urea-Glu that acts as a pharmacophore for binding to prostate-specific membrane antigen (PSMA) inhibitors. |
| PSMA-1007
PSMA-1007 is a prostate-specific membrane antigen (PSMA) ligand. |
| PSMA targeting peptide
PSMA-1 is a PSMA targeting peptide (GRFLTGGTGRLLRIS) and can be used for for targeted delivery of glucose-regulated protein (GRP)-silencing siRNAs in PCa cells. |
| Pelgifatamab
Pelgifatamab is a monoclonal antibody targeting prostate cancer-specific membrane antigen (PSMA) for prostate cancer-related studies. |
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Products are for research use only. Not for human use. We do not sell to patients.
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