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URB-597 (KDS-4103) is an orally bioavailable and selective FAAH inhibitor. URB-597 inhibits FAAH activity with an IC50s of approximately 5 nM in rat brain membranes, 0.5 nM in intact rat neurons, 3 nM in human liver microsomes. Antidepressant-like effects. Analgesic activity.
| Molecular Weight | 338.4 |
| CAS Number | 546141-08-6 |
| Solubility (25°C) | DMSO ≥ 90 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related FAAH Products |
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| JP104
JP104, a aryl carbamate, is an irreversible FAAH inhibitor with a pIC50 of ~8. |
| AM1172
AM1172 is metabolically stable anandamide uptake inhibitor and FAAH inhibitor. |
| URB937
URB937 is an orally active and peripherally restricted FAAH inhibitor (IC50=26.8 nM) and increases anandamide levels. |
| JNJ-40355003
JNJ-40355003 is a potent and selective atty acid amide hydrolase (FAAH) inhibitor. |
| N-Benzyllinolenamide
N-Benzyllinolenamide is a natural macamide isolated from Lepidium meyenii, acts as an inhibitor of fatty acid amide hydrolase (FAAH) with an IC50 of 41.8 μM. |
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