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JNJ-1661010 is a potent and selective FAAH inhibitor with IC50 of 10 nM (rat) and 12 nM (human), exhibits >100-fold selectivity for FAAH-1 when compared to FAAH-2.
| Molecular Weight | 365.45 |
| Formula | C19H19N5OS |
| CAS Number | 681136-29-8 |
| Solubility (25°C) | DMSO 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related FAAH Products |
|---|
| JP104
JP104, a aryl carbamate, is an irreversible FAAH inhibitor with a pIC50 of ~8. |
| AM1172
AM1172 is metabolically stable anandamide uptake inhibitor and FAAH inhibitor. |
| URB937
URB937 is an orally active and peripherally restricted FAAH inhibitor (IC50=26.8 nM) and increases anandamide levels. |
| JNJ-40355003
JNJ-40355003 is a potent and selective atty acid amide hydrolase (FAAH) inhibitor. |
| N-Benzyllinolenamide
N-Benzyllinolenamide is a natural macamide isolated from Lepidium meyenii, acts as an inhibitor of fatty acid amide hydrolase (FAAH) with an IC50 of 41.8 μM. |
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