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UNC6852

Cat. No. M21306

All AbMole products are for research use only, cannot be used for human consumption.

UNC6852 Structure

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Quality Control & Documentation
Biological Activity

UNC6852 is a PROTAC technology-based, selective PRC2 degradation agent containing an EED ligand and a von Hippel-Lindau ligand with an IC50 value of 247 nM for EED action.

Chemical Information
Molecular Weight 832.98
Formula C43H48N10O6S
CAS Number 2688842-08-0
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Revathi Raman, et al. Sci Rep. Knockdown screening of chromatin binding and regulatory proteins in zebrafish identified Suz12b as a regulator of tfpia and an antithrombotic drug target

[2] Frances Potjewyd, et al. Cell Chem Biol. Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader

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Keywords: UNC6852 supplier, Histone Methyltransferase, inhibitors, activators

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