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UNC 3230

Cat. No. M7457

All AbMole products are for research use only, cannot be used for human consumption.

UNC 3230 Structure
Size Price Availability Quantity
5mg USD 130  USD130 In stock
10mg USD 200  USD200 In stock
50mg USD 700  USD700 In stock
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Quality Control & Documentation
Biological Activity

UNC 3230 is a potent and selective PIP5K1C inhibitor (IC50 = 41 nM). Exhibits selectivity for PIP5K1C over PIP5K1A, the PI 3-kinase family and a panel of other kinases. Reduces PIP2 levels and LPA-induced calcium signaling in dorsal root ganglia (DRG) neurons in vitro. Reduces nociception in mouse models of chronic pain.

Chemical Information
Molecular Weight 344.43
Formula C17H20N4O2S
CAS Number 1031602-63-7
Solubility (25°C) DMSO 34.44 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] January, et al. Br J Pharmacol. Salmeterol-induced desensitisation, internalization and phosphorylation of the human β2-adrenoceptor.

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Keywords: UNC 3230 supplier, inhibitors, activators

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