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UDP-Galactose

Cat. No. M10051

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UDP-Galactose Structure
Synonym:

UDP-Gal

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Biological Activity

UDP-Galactose is a nucleotide sugar. UDP-Galactose acts as a natural agonist for Gi protein-conjugated P2Y14 receptors in the immune system with IC50 of 0.67 μM for hP2Y14. UDP-Gal can block BALB/3T12 cell development. UDP-Gal has been used as a component in galactosyltransferase labeling buffer to prelabel terminal N-acetylglucosamine (GlcNAc) on immunoglobulin chains. It has also been used as a component in Hyp O-galactosyltransferase (HPGT) assay.

Chemical Information
Molecular Weight 566.3
Formula C15H24N2O17P2
CAS Number 2956-16-3
Storage -20°C, protect from light, dry, sealed
References

[1] Shinya Fushinobu. Curr Opin Chem Biol. Molecular evolution and functional divergence of UDP-hexose 4-epimerases

[2] Yuzhou Fan, et al. Biotechnol Bioeng. Amino acid and glucose metabolism in fed-batch CHO cell culture affects antibody production and glycosylation

[3] Yang Zou, et al. Carbohydr Res. One-pot three-enzyme synthesis of UDP-Glc, UDP-Gal, and their derivatives

[4] Jennifer M I Daenzer, et al. PLoS Genet. UDP-galactose 4'-epimerase activities toward UDP-Gal and UDP-GalNAc play different roles in the development of Drosophila melanogaster

[5] Dorota Maszczak-Seneczko, et al. Acta Biochim Pol. Subcellular localization of UDP-GlcNAc, UDP-Gal and SLC35B4 transporters

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Keywords: UDP-Galactose, UDP-Gal supplier, Metabolite/Endogenous Metabolite, inhibitors, activators

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