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TX2-121-1, a potent and selective Her3 (ErbB3) bivalent ligand, can induce degradation of Her3 with an IC50 of 49 nM. TX2-121-1 can inhibit Her3-dependent signaling.
| Molecular Weight | 716.91 |
| Formula | C42H52N8O3 |
| CAS Number | 1603845-42-6 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[2] Ting Xie, et al. Nat Chem Biol. Pharmacological targeting of the pseudokinase Her3
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