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Tuvusertib

Cat. No. M54526

All AbMole products are for research use only, cannot be used for human consumption.

Tuvusertib Structure
Synonym:

M1774; ATR inhibitor 1

Size Price Availability Quantity
5mg USD 170  USD170 In stock
10mg USD 270  USD270 In stock
25mg USD 500  USD500 In stock
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Quality Control & Documentation
Biological Activity

Tuvusertib is a selective and orally active ATR inhibitor that kills tumor cells by preventing the repair of damaged DNA with a Ki value below 1 μΜ.

Chemical Information
Molecular Weight 370.32
Formula C16H12F2N8O
CAS Number 1613200-51-3
Form Solid
Solubility (25°C) DMSO 5 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Related ATM/ATR Products
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ART0380 is a potent and selective ATR kinase inhibitor.

KU 59403 

KU 59403 is a potent ATM inhibitor, with IC50 values of 3 nM, 9.1 μM and 10 μM for ATM, DNA-PK and PI3K, respectively.

SKLB-197 

SKLB-197 showed an IC50 value of 0.013 μM against ATR but very weak or no activity against other 402 protein kinases.

ATR-IN-4 

ATR-IN-4 is a potent ATR (Ataxia telangiectasia mutated gene Rad 3-associated kinase) inhibitor.

M3541 

M3541 is a potent, ATP-competitive and selective ATM inhibitor with an IC50 of 0.25 nM.

  Catalog
Abmole Inhibitor Catalog




Keywords: Tuvusertib, M1774; ATR inhibitor 1 supplier, ATM/ATR, inhibitors, activators

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