Free shipping on all orders over $ 500
TRULI inhibits Lats1 and Lats2 with IC50 of 0.2 nM, inhibits Yap phosphorylation, induces cell proliferation of multiple cell lines and tissues, and promotes the initial stage of proliferation and regeneration of sensory receptors in the inner ear.
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
| Molecular Weight | 334.39 |
| Formula | C18H14N4OS |
| CAS Number | 1424635-83-5 |
| Purity | >99% |
| Solubility | DMSO ≥ 60 mg/mL |
| Storage | at -20°C |
| Related Products |
|---|
| RP-6306
RP-6306 is the only inhibitor of PKMYT1 currently available in the clinic, which is synthetically fatal to CCNE1 amplification, FBXW7 deletion or other specific mutations. |
| Myxothiazol
Myxothiazol, an antifungal antibiotic, is an inhibitor of mitochondrial electron transport chain complex III (Complex III or Bc1 complex). |
| WGA
Wheat agglutinin (WGA) is isolated from wheat (Triticum vulgaris, Weat germ), WGA selectively binds to glycoproteins and glycolipids of n-acetylglucosamine (GlcNAc) and n-acetylneuraminine (sialic acid) residues. |
| Antide
Sequence：Ac-D2Nal-DCpa-DPal-Ser-Lys(nicotinoyl)-DLys(nicotinoyl)-Leu-Lys(isopropyl)-Pro-DAla-NH2 |
| NE-CARBOXYMETHYL-L-LYSINE
NE-CARBOXYMETHYL-L-LYSINE |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.
