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Trametiglue

Cat. No. M42141

All AbMole products are for research use only, cannot be used for human consumption.

Trametiglue Structure

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Quality Control & Documentation
Biological Activity

Trametiglue, a derivative of Trametinib, targets both KSR-MEK and RAF-MEK with unprecedented potency and selectivity via unique interfacial binding interactions.

Chemical Information
Molecular Weight 666.46
Formula C25H24FIN6O5S
CAS Number 2666940-97-0
Form Solid
Solubility (25°C) DMSO 90 mg/mL (ultrasonic and warming)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Zaigham M Khan et al. Nature. Structural basis for the action of the drug trametinib at KSR-bound MEK

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  Catalog
Abmole Inhibitor Catalog




Keywords: Trametiglue supplier, MEK, inhibitors, activators

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