TMRM Perchlorate is a cell-permeant cationic lipophilic red fluorescent dye (λex=530 nm, λem=592 nm).
J Cell Mol Med. 2022 Jul;26(14):4048-4060.
BRAF V600E protect from cell death via inhibition of the mitochondrial permeability transition in papillary and anaplastic thyroid cancers
TMRM Perchlorate purchased from AbMole
|Body Surface Area (m2)||0.007||0.025||0.15||0.05||0.02||0.5|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
|Solubility||DMSO ≥ 26 mg/mL|
|Storage||2-8°C, dry, protect from light, sealed|
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Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride is an oxygen-sensitive fluorescence indicator widely used as a probe for luminescence detection and oxygen quantification. The maximum absorption wavelength is max 455 nm and the maximum luminescence is λmax 613 nm.
|FeRhoNox-1 (Fe2+ indicator)
FeRhoNox-1, also known as RhoNox-1, is an active fluorescent probe that specifically detects unstable iron (1) ions (Fe2+). After the reaction of -denier with Fe2+, -orange (red) fluorescent products are irreversibly generated. (Absmax= 540nm, FLmax= 575nm).
CMFDA is a cell-permeable fluorescent probe that can be used as a cellular tracer. CMFDA can be cleaved by non-specific esterases common to living cells, producing a fluorescent compound, fluorescein, visible using a fluorescent microscope.
Lyso-Tracker Red is an eosinophilic fluorescent probe with a maximum excitation wavelength of 577nm and a maximum emission wavelength of 590nm. Lyso-Tracker Red must be at very low concentrations (usually about 50nM) to achieve excellent selectivity.
|FITC-Dextran (MW 10000)
FITC-Dextran (MW 10000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm).
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