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TMA-DPH

Cat. No. M11517

All AbMole products are for research use only, cannot be used for human consumption.

TMA-DPH Structure
Size Price Availability Quantity
1mg USD 110  USD110 In stock
5mg USD 150  USD150 In stock
10mg USD 240  USD240 In stock
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Quality Control & Documentation
Biological Activity

Tma-dph contains a cationic trimethylammonium substitute that can be used as a surface anchor locator to improve the localization of the fluorescent probe DPH in the membrane. By analyzing the fluorescence polarization values of TMA-DPH in the plasma membrane and membrane substructures, the fluidity of the cell membrane can be determined. The maximum excitation/emission wavelength is 355nm/430nm, and it is blue fluorescent and stored at room temperature away from light.

*The compound is unstable in solutions, freshly prepared is recommended

Chemical Information
Molecular Weight 461.62
Formula C28H31NO3S
CAS Number 115534-33-3
Solubility (25°C) DMSO 6 mg/mL
Storage -20°C, protect from light, dry, sealed
References

[1] Antnio M T M do Canto, et al. Biochim Biophys Acta. Diphenylhexatriene membrane probes DPH and TMA-DPH: A comparative molecular dynamics simulation study

[2] Brad Chazotte. Cold Spring Harb Protoc. Labeling the plasma membrane with TMA-DPH

[3] C Saldanha, et al. J Membr Biol. Fluorescent probes DPH, TMA-DPH and C17-HC induce erythrocyte exovesiculation

[4] G Ferretti, et al. Membr Biochem. Properties of a phosphatidylcholine derivative of diphenyl hexatriene (DPH-PC) in lymphocyte membranes. A comparison with DPH and the cationic derivative TMA-DPH using static and dynamic fluorescence

[5] A Benedetti, et al. J Gastroenterol Hepatol. Plasma membrane fluidity in isolated rat hepatocytes: comparative study using DPH and TMA-DPH as fluorescent probes

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