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Tiragolumab is an immune checkpoint inhibitor that binds to T-cell immunoglobulin and the structural domain of ITIM (TIGIT), targeting TIGIT with an intact Fc region.TIGIT is a novel inhibitory immune checkpoint expressed primarily on the surface of T-cells and natural killer (NK) cells, which suppresses an organism's immune response to cancer. It can be used in studies related to solid tumors.
| CAS Number | 1918185-84-8 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[3] No authors listed. Cancer Discov. Tiragolumab Results Cast Shadow on TIGIT Pipeline
[4] Peter Sidaway. Nat Rev Clin Oncol. Tiragolumab active in PD-L1+ NSCLC
| Related TIGIT Products |
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| Dargistotug
Dargistotug is a fully human IgG1 monoclonal antibody targeting T-cell immunoglobulin and the ITIM structural domain (TIGIT) that induces an immune response targeting cancer cells by blocking the TIGIT pathway. |
| Tamgiblimab
Tamgiblimab (IBI939) is a fully human monoclonal antibody targeting T-cell immunoreceptor with immunoglobulin and ITIM domains (TIGIT). Tamgiblimab has anticancer effects. |
| Domvanalimab
Domvanalimab (AB154) is an anti-TIGIT humanized monoclonal antibody. Domvanalimab binds human TIGIT9 and blocks the TIGIT-CD155 interaction. Domvanalimab can be used in research of cancer. |
| Ociperlimab
Ociperlimab is a humanized IgG1 anti-TIGIT antibody. Ociperlimab binds to the extracellular domain of human TIGIT with high affinity (KD = 0.135 nM). Ociperlimab blocks the interaction between TIGIT and its ligands PVR or PVR-L2. Ociperlimab can be used in research of cancer. |
| Vibostolimab
Vibostolimab is an anti-TIGIT (T cell immunoglobulin and ITIM domain) monoclonal antibody. Vibostolimab shows antitumor activity, and can be used in non-small cell lung cancer (NSCLC) and melanoma research. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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